Significados de transform activity em inglês

A mutation in the putative DNA-binding region of ets-2 abolished transforming activity.

This sequence is the best candidate for suppressing transforming activity of c-raf.

TH-20, which was isolated from soil samples on which ginseng grown, exhibited effective ginsenoside- transforming activity.

We observed that small deletions within the CREB-binding domain completely abolished transforming activity in RK3E epithelial cells.

Here, we show robust transforming activity of sTAg in vivo in a panel of transgenic mouse models.

Three large T mutants displayed transforming activity that was greater than that of wild type and are called supertransforming mutants.

Since these molecules also bind to albumin, this may also explain the hyphal transforming activity in serum that associates with albumin.

We propose that the PDGF receptor is an important cellular intermediate in the transforming activity of the bovine papillomavirus E5 protein.

Transforming activity in the radiation and NMU-induced tumors was analyzed using both the nude mouse tumorigenicity assay and the focus-forming assay.

Previous studies have revealed that PC-1 possesses transforming activity and confers malignant phenotypes to mouse NIH3T3 cells.

Moreover, the loss of transforming activity following mutation of the sTAg Fbxw7 binding domain identifies this domain as crucial for in vivo transformation.

We show that the motif crucial for ets-2 transactivation capability is necessary for transforming activity in Rat-1 cells.

Interaction of p60v-src with the plasma membrane is essential for transforming activity, and is mediated by association with a membrane-bound Src receptor protein.

Amplified fragments from individual primary transformants were recloned into intact FMS vector plasmids, and those with transforming activity were subjected to nucleotide sequence analysis.

A transactivation-deficient mutant of ets-2 failed to transform Rat-1 cells and suppressed the transforming activity of coexpressed wild-type ets-2.

The TPR-MET fusion protein contains constitutively elevated Met tyrosine kinase activity and constitutes an ideal model to study the transforming activity of the Met kinase.