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The untitled comedy, from writer Laura House, has received a script commitment.
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Sherman-Palladino will write and executive produce an untitled comedy-drama for the cable network.
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In other pilot news, ABC has picked up an untitled comedy pilot by Victoria Pile.
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Boston and Amy Yasbeck have landed lead roles on ABC's untitled comedy pilot set in a chaotic Phoenix TV newsroom.
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In another sign the show was on its way out, "Will & Grace" alumnus McCormack last month booked an untitled comedy pilot at ABC.
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Later this month she begins shooting her first post-"Up in the Air" project, an untitled comedy with Seth Rogen and James McAvoy for Mandate Pictures.