Anuran and urodele amphibians develop spontaneous neoplasms in all major organ systems with the integumentary system a frequent target.
2
A central theme concerning the epimorphic regenerative potential of urodele amphibian appendages is that limb regeneration in the adult parallels larval limb development.
3
Anurans and urodeles have spontaneous viral-associated tumors, the biological behavior of which is temperature-related.