Significados de wide studies em inglês

This platform constitutes a valuable tool for future genome- wide studies involving mouse models of disease.

The effects of PER3 variants on many phenotypes have been investigated in targeted and genome- wide studies.

We also attempted to replicate prior findings from genome- wide studies in non-Hispanic populations in Hispanic cohorts.

Insights have come from recent genome- wide studies, which highlight the importance of tissue-specific transcription factors and epigenetics.

We performed two case-control genome- wide studies using two accepted cut-offs for defining individuals as overweight or obese.

Recent genome- wide studies have provided initial evidence that CNVs at other loci may also be associated with schizophrenia.

The approach is computationally efficient, scales to genome- wide studies, and is applicable to correlated symptom data of arbitrary dimension.

In addition, we have validated cis-acting variants in over 20 genes linked with common disease susceptibility in recent genome- wide studies.

For Crohn's disease, in particular, the link between deprivation and increased hospitalization and mortality observed from world- wide studies is alarming.

Genome- wide studies have detected numerous variants associated with disease as well as common gene fusions and expression 'signatures' in prostate tumours.

The complete sequencing the human genome and recent analytical advances have provided the opportunity to perform genome- wide studies of human variation.

Genome- wide studies of the complete panel have included exome sequencing, karyotyping, and copy number analyses but have not targeted repetitive sequences.

Background: Multiple recent genome- wide studies of single nucleotide polymorphisms (SNP) reported associations between candidate chromosome loci and lung cancer susceptibility.

Genome- wide studies have defined cell type-specific patterns of DNA methylation that are important for regulating gene expression in both normal development and disease.

Results: Despite some limitations, these initial genome- wide studies of CNVs provide replicated associations of schizophrenia with rare 1q21.1 and 15q13.3 deletions.