Значения для термина "affect siblings" отсутствуют.
1 We have characterized a family comprising two affected siblings born to healthy parents.
2 Three affected siblings had the characteristic features of Setleis syndrome.
3 Three affected siblings had characteristic white matter abnormalities and presented with progressive neurological decline.
4 Sanger sequencing confirmed the presence of the homozygous mutation in the other three affected siblings .
5 It was observed that the segregation of NRAMP1 haplotypes into affected siblings was significantly nonrandom.
6 The presence of psychotic symptoms in AD confers increased risk of similar symptoms to affected siblings .
7 Purpose: We revisited 42 families with two or more cleft- affected siblings who participated in previous studies.
8 Gender was randomly distributed among bipolar sibships, demonstrating the absence of gender resemblance among affected siblings .
9 In order to test this hypothesis, we studied 102 sibships with two or more affected siblings .
10 We observed gonosomal mosaicism for a variant in PAX3 in an asymptomatic father of two affected siblings .
11 To identify the causative gene(s), exome sequencing was performed in a family with two affected siblings .
12 To assess the significance of secondary cases we compare the incidence of affected siblings between probands and their spouses.
13 No intrafamilial correlation was found for the gender of affected siblings , suggesting that familial vulnerability factors are not gender-specific.
14 The null hypothesis of a random distribution of affected siblings was rejected (P=0.005).
15 Conclusions: We have identified mutations in PLA2G4A as a cause of CMUSE in two affected siblings .
16 Sanger sequencing confirmed the presence of this variant in a homozygous state in the two affected siblings , while both parents were heterozygous.
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