CHDP-1 is anchored to the cortex through its amphipathic helix.

An application to the envelope protein of HIV finds an unexpected long amphipathic helix in gp41.

This demonstrates that the positions of charged residues in the amphipathic helix play an important role in lecithin:cholesterol acyltransferase activation.

The small GTPase Arf1 and related proteins have the ability to remodel membranes by insertion of an amphipathic helix into the membrane.