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Recent evidence suggests that cellular senescence also may be involved in aging.
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EWS deficiency leads to impaired development and early senescence through unknown mechanisms.
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It has been suggested that this process is responsible for cellular senescence.
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However, the signaling mechanism linking obesity with age-related vascular senescence is unknown.
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Premature and absolute loss of PTEN activity usually tends to cellular senescence.
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An accelerated rate of biologicalaging could contribute to this increased risk.
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Problem: Epigenetic age indices are markers of biologicalaging determined from DNA methylation patterns.
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A widely used marker of biologicalaging is telomere length.
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This study assessed the contribution of genetic and nongenetic factors to biologicalaging in American Caucasians.
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As the biologicalaging process demonstrates gender-specific characteristics, the analyses were performed separately in males and female.
Использование термина biological ageing на английском
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He sees it as a matter of re-educating the public and health authorities to see biologicalageing in a new light.
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Thus, drift emerges as a promising biomarker for premature or biologicalageing, and could potentially be used in geriatrics for disease risk prediction.