Passageways by which air passes through the nose or mouth to the alveoli of the lungs.
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Notably, repair of the terminal-bronchiole epithelium was markedly promoted after transplantation of the differentiated iPSCs.
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Furthermore, ABX mice exhibited severe bronchiole epithelial degeneration and increased host mortality after influenza virus infection.
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The farther an alveolar duct bifurcation was from its terminal bronchiole, the less asbestos were observed.
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Thus, OA exposure induces structural changes in bronchiole ASM content and in agonist responsiveness ex vivo that resemble remodeling in asthma.
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DEX induces the expression of calcium-related proteins through the glucocorticoid receptor-mediated pathway and may involve decreased mucin secretion in the bronchiole.
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Pdk4 protein levels were also significantly increased in adult mouse lungs exposed to hyperoxia and were localized mainly to the epithelium of terminal bronchiole.
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Alternatively, only 2 of 18 tumors and 8 of 14 adjacent nonmalignant bronchiole epithelium regions demonstrated negative to low levels of TDE2 signals.
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The smaller nuclei of human bronchioles were comparable to those of alveolar cells.
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The outer wall of small membranous bronchioles is the main site of inflammatory changes in FA.
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Both groups had normal alveolar morphology, whereas only group A had injured respiratory and membranous bronchioles.
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'Just one thing: evidence of sand in the terminal bronchioles and alveoli.
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However, MUC5B was also extensively expressed in superficial epithelia throughout the airways except for the terminal bronchioles.
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Under all conditions tested, the majority of Clara cells in the bronchioles both self-renews and generates ciliated cells.
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Inflammatory cells were seen around bronchioles and capillaries in model and asthma groups but not the NS group.
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Analogously, Gpx3 shifts from the basement membranes underlying the bronchioles and blood vessels to the alveoli, thus maintaining balanced expression.
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These tumours arise from subsegmental or distal bronchioles, are usually well circumscribed and encapsulated, and contain varying amounts of spindle cells.