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Methods: Case-control analyses were performed to investigate the association between clomiphene exposure and hypospadias.
2
The concentrations of HCG were significantly reduced in clomiphene pregnancies compared to natural pregnancies.
3
Further research is needed to clarify when clomiphene citrate is indicated in the treatment of male infertility.
4
Interventions: Ovulation was induced with clomiphene, metformin, or the combination of both for up to six cycles or conception.
5
It says a more likely culprit is a fertility drug called clomiphene, which can be prescribed by any doctor without monitoring.
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The available evidence reveals mixed results and suggests that clomiphene citrate may be appropriate for the management of male infertility in specific clinical scenarios.
7
Spontaneous abortion risk was increased among women reporting previous spontaneous abortions and ART attempts, and among women who used clomiphene or zygote intrafallopian transfer.
8
The researchers did find an increased risk of breast cancer among a small subset of women who were prescribed the highest doses of clomiphene, however.
9
Conclusion(s): Our findings of increased risk of ovarian cancer after gonadotropins and of borderline tumors after clomiphene treatment need to be interpreted with caution.
10
About 38 percent of the study participants were exposed to the fertility drug clomiphene and about 10 percent were exposed to drugs known as gonadotropins.
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Clomiphene citrate (CC) is known to possess dual actions as an estrogen agonist and an estrogen antagonist.
12
Clomiphene citrate, a selective estrogen receptor modulator, has been used to treat infertility in women and men for 50 years.
13
Methods: Case-control analyses were performed to investigate the association between clomiphene exposure and hypospadias.
14
The concentrations of HCG were significantly reduced in clomiphene pregnancies compared to natural pregnancies.
15
Further research is needed to clarify when clomiphene citrate is indicated in the treatment of male infertility.
16
Interventions: Ovulation was induced with clomiphene, metformin, or the combination of both for up to six cycles or conception.