1
Mammalian genomes contain highly conserved sequences that are not functionally transcribed.
2
They also provide indications for potential gene sequences, identifiable as evolutionarily conserved sequences.
3
Substantial portions of conserved sequence are dispensable, indicating the presence of sequence redundancy.
4
However, the functional significance of this conserved sequence is unknown.
5
Both factors have tandem ADs that were identified by conserved sequence and functional studies.
6
Using the same procedure, the analysis was extended to other residues within the conserved sequence.
7
Identification of these conserved sequences will help elucidate important molecular mechanisms or pathways common to many species.
8
Several homologous proteins with highly conserved sequences were identified and quantified in A. fumigatus and C. posadasii.
9
Early efforts focused primarily on screening of cDNA libraries, identification of evolutionarily conserved sequences, and northern blot hybridization.
10
Inteins are protein-splicing elements, most of which contain conserved sequence blocks that define a family of homing endonucleases.
11
We observed conserved sequence motifs and structural elements among 1762 NDH-2s.
12
Apicoplast TPs do not contain a conserved sequence motif; therefore, we asked whether they contain an essential structural motif.
13
To gain functional insight into these conserved sequences, we genetically and molecularly characterized 14 point mutations in Drosophila fringe.
14
The HRC enhancer contains a small, highly conserved sequence that is required for expression in all three muscle lineages.
15
Furthermore, these epitopes are highly conserved sequences within KSHV isolates from a specific strain but are not conserved between different strains.
16
Analysis of the predicted amino acid sequence revealed the presence of a P-loop motif, a conserved sequence found in nucleotide-binding proteins.