Meanings of cytotoxic agent in английском

The cytotoxic agent temozolomide has also demonstrated activity in patients with advanced sarcoma.

Pemetrexed is the first third-generation cytotoxic agent tolerable at full dose in this setting.

Current palliative therapeutic approaches mostly focused on evaluating chemotherapy regimens in which gemcitabine is combined with a second cytotoxic agent.

Clinicians should be aware of the potential acute fatal side effect of this otherwise well tolerated and widely used cytotoxic agent.

Pancreatic cancer has proven to be chemo-resistant, with gemcitabine being the only cytotoxic agent approved for advanced pancreatic cancer since 1996.

The cumulative experience of single-agent paclitaxel in advanced, metastatic NSCLC suggests that it is a highly active cytotoxic agent in this setting.

The proposed method has been validated and, subsequently, implemented in a phase I clinical trial for pharmacokinetic evaluation of the new cytotoxic agent.

To the authors' knowledge, there have been no published reports of this phenomenon after the administration of the widely applied cytotoxic agent raltitrexed.

We believe that this 3 step induction process is common for any cytotoxic agent that induces chromosomal aberrations after DNA replication has been inhibited.

Then, the changes in the permeability of the cell membrane to a cytotoxic agent (bleomycin) were assessed by a cloning efficacy test.

A number of cytotoxic agents, alone and in combination, have shown activity.

Second and 3rd trimester exposure to cytotoxic agents may predispose to placental underdevelopment.

Studies incorporating additional cytotoxic agents demonstrate increased morbidity with little benefit.

Background: The search for natural products as potential cytotoxic agents has yielded promising candidates.

While chemotherapies with cytotoxic agents have demonstrated initial treatment response, most tumors recur quickly.

Antitumor effects were equal or superior to that of several clinically approved cytotoxic agents.