These mAbs demonstrated potent neutralizing activities against both pseudo and live Ebola virus independent of complement.

Conclusions: Once daily TMC435 given orally was generally safe and well tolerated and demonstrated potent antiviral activity.

We and others have demonstrated potent sympatho-stimulatory actions of nesfatin-1 in brain and the potential physiologic relevance of those effects.

The antifungal compound demonstrated potent antifungal activities against a broad panel of fungal plant and animal pathogens, as well as two Pythium spp.

Subsequent SAR campaign provided a potent and selective pan Aurora inhibitor, which demonstrated potent target modulation and antiproliferative effects in the pancreatic cell line, MIAPaCa-2.