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Patients with diabetes may have kidney diseases other than the diabetickidneydisease.
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Thus, HIF stabilization counteracts alterations in renal energy metabolism occurring in incipient diabetickidneydisease.
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Context: Impaired vitamin D metabolism may contribute to the development and progression of diabetickidneydisease.
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Aim: To analyse the efficacy and safety of endothelin receptor antagonists for people with diabetickidneydisease.
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Purpose: Renal inflammatory response is involved in the development and progression of diabetickidneydisease (DKD).
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Also, HO-1 expression is important in the pathogenesis of hypertension, diabetickidneydisease, and progression to end-stage renal disease.
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Identifying these patients early and addressing modifiable risk factors is central to delaying renal complications such as diabetickidneydisease.
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The protein kinase C (PKC)-beta isoform has been implicated to play a pivotal role in the development of diabetickidneydisease.
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Methods: Randomized controlled trials comparing endothelin receptor antagonists with placebo in people with diabetickidneydisease were identified through PubMed, Embase and the Cochrane Library.
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Previous studies suggest that systemic metabolic disorders such as hyperglycemia and dyslipidemia cause alterations of renal metabolism, leading to renal dysfunction including diabetickidneydisease.
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Diabetickidneydisease (DKD) is a serious disease that presents a major health problem worldwide.
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Diabetickidneydisease is a microvascular complication that is observed in a minority of patients with long-standing hyperglycemia.
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Diabetickidneydisease (DKD) is a life-limiting condition characterized by progressive and irreversible loss of renal function.
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Diabetickidneydisease causes significant morbidity and mortality among people with type 1 diabetes (T1D).
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Diabetickidneydisease (DKD) remains the leading cause of end-stage renal disease (ESRD) and is therefore a major burden on the healthcare system.