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However, the impact of diabetes on survival in patients treated with fibrinolyticagents is still undefined.
2
Attempts to improve thrombolytic treatment include the search for better fibrinolyticagents and more effective adjunctive therapies.
3
The latter might in part be explained by increasing use concomitant antiplatelet therapy, pre-hospital treatment and fibrin-specific fibrinolyticagents.
4
Conclusions: A history of diabetes is associated with a worse prognosis after myocardial infarction, even in patients treated with fibrinolyticagents.
5
Methods: We analyzed prevalence and prognostic significance of a history of diabetes in patients enrolled in the GISSI-2 study, all of whom received fibrinolyticagents.
6
Plasmin is the prototype of a distinct class of "direct-acting" fibrinolyticagents, with biochemical and physiological attributes that are favorable for catheter-delivered thrombolytic therapy.