Hypertriglyceridemic patients showed significantly higher triglyceride area and a slower CM fractional catabolic rate.

Kinetic studies demonstrated a significant dose-dependent increase in the fractional catabolic rate of HDL-apolipoprotein in EL-overexpressing mice.

IgG has the longest survival time in the circulation of the Ig classes and the lowest fractional catabolic rate.

Whereas obesity did not influence apoE kinetic parameters in itself, insulin resistance may lead to an increase in VLDL apoE production and fractional catabolic rates.

The aim of the study was to test the hypothesis that these abnormalities were related to an increase of HDL-apoA-I fractional catabolic rate (FCR).