Background and objectives: The pathophysiology of functional dyspepsia is not yet completely known.

Aim: To assess the association between depression and functional dyspepsia.

We aimed to evaluate whether quality of life is poorer in patients with functional dyspepsia.

Mental health, social functioning, and health perception also tended to be poorer in functional dyspepsia.

Antidepressants are commonly prescribed for patients with functional dyspepsia.

Duodenal hyperpermeability and low-grade inflammation in functional dyspepsia is potentially related to duodenal acid exposure.

Conclusions: In patients with functional dyspepsia, resting cerebral glycometabolism differs significantly from that of healthy subjects.

Aim: To evaluate the effects of asimadoline on satiation volume and postchallenge symptoms in functional dyspepsia.

A consecutive sample of 73 patients with functional dyspepsia completed a validated questionnaire prior to endoscopy.

However, its effect on satiation in functional dyspepsia is unclear, and any symptom benefit has not been explored.

Other works link this genetic factor to functional dyspepsia, and these exciting preliminary lines of evidence are reviewed.

Objectives: Acupuncture is a commonly used therapy for treating functional dyspepsia (FD), although the mechanism remains unclear.

Discussion: The adjustment for the gender, age and marital status variables confirmed the association between functional dyspepsia and depression.

Objectives: To determine the frequency, demographics, and clinical characteristics associated with duodenal disaccharidase deficiencies in children with functional dyspepsia.

Conclusion: Asimadoline overall did not significantly alter maximum-tolerated volume, symptoms postnutrient challenge or symptoms over 8 weeks in functional dyspepsia.

Conclusions: The results show that both CNS and classic drugs are associated with a significant pain reduction in functional dyspepsia.