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Cohen himself published some of the early work on glucocorticoidresistance.
2
Other research has shown that this acts as a surrogate measure of glucocorticoidresistance.
3
While animal work showing that chronic stress affects glucocorticoidresistance is persuasive, it is not definitive.
4
Cohen realised that data from two of his previous studies could be used to test this glucocorticoidresistance theory.
5
He knows, for example, of another group of researchers planning a study of the role of glucocorticoidresistance in asthma.
6
Familial glucocorticoidresistance is a hypertensive, hyperandrogenic disorder characterized by increased serum cortisol concentrations in the absence of stigmata of Cushing's syndrome.
7
These results suggest that glucocorticoidresistance in this family is due to a point mutation in the steroid-binding domain of the glucocorticoid receptor.
8
In a second study, Cohen had made direct measurements of glucocorticoidresistance in a group of 79 subjects before exposure to cold viruses.
9
The kinetic data obtained argue against the involvement of 11 beta-hydroxysteroid dehydrogenase as a modulating factor for the glucocorticoidresistance observed in guinea pigs.
10
The experiment revealed that prolonged stress is correlated not only with the likelihood of developing a cold, but also with higher levels of glucocorticoidresistance.