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Использование термина glycoside hydrolases на английском
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Conclusions: This work provides the foundation for further comparative and functional analyses of plant glycosidehydrolases.
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Sequence analysis reveals approximately 130 predicted glycosidehydrolases that target the major structural and storage plant polysaccharides.
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The major advance of our study was the discovery of active-yet-uncultivated soil microorganisms and enrichment of their glycosidehydrolases.
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Genes encoding glycosidehydrolases are found in a wide range of organisms, from archea to animals, and are relatively abundant in plant genomes.
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Evaluating these enzymes as potential therapeutics, we demonstrate that these glycosidehydrolases selectively target and degrade the exopolysaccharide component of the biofilm matrix.
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These findings suggest that glycosidehydrolases can exhibit activity against diverse microorganisms and may be useful as therapeutic agents by degrading biofilms and attenuating virulence.