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1 Two patients developed grade 3 proteinuria that resolved after a treatment break.
2 The commonest post-operative diagnosis was CIN grade 3 in all age groups.
3 Dose-limiting toxicities were defined as grade 3 esophageal, cardiac, or pulmonary toxicity.
4 MRC grade 3 is a critical point of indication for application of MEPs.
5 The incidence of any- grade and grade 3 or greater adverse events was manageable.
6 The incidence of grade 3 or higher toxicities was greater with combination therapy.
7 No grade 3 or important clinical, hematologic, or biochemical toxicities occurred.
8 Nodal involvement was associated with serous histology and grade 3 tumor.
9 Dose-related grade 3 fatigue and vomiting were observed but these were not dose-limiting.
10 Only one grade 3 of subacute toxicity for thrombocytopenia was noted.
11 This component was diagnostic of grade 3 papillary renal cell carcinoma.
12 No grade 3+ adverse events potentially related to study medication were observed.
13 PCI was also associated with a modest increase in grade 3 or higher AEs.
14 No grade 3 or higher hematologic adverse events were observed.
15 No patients developed late grade 3 GI or GU toxicity.
16 One patient was taken off study for grade 3 neuropathy.
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