We found clozapine increases grooming behavior as early as 30 wk.

Tumor-bearing rats developed heat and tactile hypersensitivity along with increased spontaneous grooming behavior.

Hormonal variation during the different phases of the estrous cycle of female rats also changes the grooming behavior.

Adult rats were evaluated for signs of pain and distress, including changes in posture, facial signs, and grooming behavior.

These findings indicate that chronic social stress modulates grooming behavior in mice, thus illustrating the importance of grooming phenotypes for neurobehavioral stress research.

Grooming behaviors were moderately associated with anxiolytic-like behaviors in the elevated plus maze test.

Grooming behavior is an adaptation to a stressful environment that can vary in accordance with stress intensity.