Atypical carcinoid tumor had high malignancy and poor prognosis.

All phenotype B lymphomas of intermediate or high malignancy grade according to the Working Formulation are difficult to classify histologically.

Glioma is still difficult to treat because of its high malignancy, high recurrence rate, and high resistance to anticancer drugs.

These results indicate that the synchronous expression of TGF alpha and c-Ha-ras p21 plays an important role in high malignancy of gastric carcinomas.