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Published data concerning the effects of hypertonicity on cell motility have often been controversial.
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The effects of hypertonicity on cell kinetics of EUE cells in culture have been investigated.
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The reduction of COX-2 expression was associated with greatly reduced viability of dominant-negative JNK-2-expressing cells during hypertonicity treatment.
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PMID: 10930430 The reduction of COX-2 expression was associated with greatly reduced viability of dominant-negative JNK-2-expressing cells during hypertonicity treatment.
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Hypertonicity-stimulated COX-2 protein expression was significantly reduced in dominant-negative JNK-2-expressing cells and was unchanged in dominant-negative JNK-1- and JNK-3-expressing cells compared with controls.