Значения термина impair cell на английском

Importantly, expression of mutant versions of cyclin F that cannot be phosphorylated by AKT impair cell-cycle entry.

MED1 defects (much like MMR defects) may impair cell cycle arrest and apoptosis induced by DNA damage.

Control experiments using corresponding Bcl-2 sense or nonsense oligonucleotides did not significantly impair cell survival or growth of GM-colony-forming unit.

Alterations in O-GlcNAc addition or removal (cycling) impair cell cycle progression and cytokinesis, but the mechanisms are not well understood.

Because toxicity was independent of enzyme catalysis, the inappropriate coordination of N-terminal and linker domains may induce aberrant Top1-protein interactions to impair cell growth.

We found that reduced CD18 expression impaired cell-cell contact between Tregs and DCs.

Moreover, the loss of Atg6 impairs cell polarity.

YAP reduction significantly impairs cell migration and invasion.

Disruption of one of these genes abolishes or severely impairs cell traversal without affecting other types of invasive motility.

Patients who had multiple skin cancers (three or more) were studied to determine whether they had impaired cell-mediated immunity (CMI).

Using real-time behavioral monitoring in a closed-loop sleep deprivation system, we find that sleep loss in larvae impairs cell division of neural progenitors.

Functionally, we found that HOTAIR overexpression increases breast cancer cell proliferation, whereas its depletion significantly impairs cell survival and abolishes tamoxifen-resistant cell growth.

Using the small-molecule inhibitor EPZ015666, we show that PRMT5 inhibition impairs cell proliferation in a subset of TNBC cell lines.

In isolated hearts of normal rats, perfusion of IL-1β not only increases pS368 Cx43 but also impairs cell-to-cell communication and prolongs QRS duration.