Smaller LV dimension and increased LV ejection fraction were seen in SCF-treated animals.

With HF, there was increased LV chamber stiffness and slow relaxation.

Results: Subjects with SCD had larger left and right atrial volumes and increased LV mass compared with controls.

Thus, in this NIDDM study population, male patients with the DD genotype are independently associated with an increased LV mass.

In conclusion, more severe nocturnal hypoxemia, increasing systolic blood pressure, and body mass index are all independently associated with increased LV mass.

Older patients have increased LV size after MI compared with younger patients, possibly related to age-related decreases in aortic distensibility affecting LV remodeling.