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What is a kidneycyst and should I worry about kidney cancer?
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Defects of the PCP pathway have been found to cause kidneycyst formation.
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Robotic surgery on a kidneycyst.
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Dysregulated miRNA expression is observed in PKD, but whether miRNAs are directly involved in kidneycyst formation and growth is not known.
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Here our aim was to investigate the effect of Ganoderma triterpenes (GT) on the development of kidneycysts.
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Kidneycysts occur following inactivation of polycystins in otherwise intact cilia or following complete removal of cilia by inactivation of intraflagellar transport-related proteins.
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ORC1-deficiency confers defects anticipated to arise from impaired cilia function such as formation of oedema, kidneycysts, curved bodies and left-right asymmetry defects.