Значения термина orally bioavailable на английском

Olinciguat was orally bioavailable and predominantly cleared by the liver in rats.

One reason we switched was because the Glaxo compound was not orally bioavailable.

E913 and its analogs are acid-resistant and orally bioavailable in rodents.

The desired outcome of the study was to identify an orally bioavailable TF-VIIa inhibitor.

Little progress has been reported in developing longer acting or orally bioavailable fusion inhibitors.

Conclusions and implications: Methnaridine is an orally bioavailable, fast-acting and long-lasting agent with excellent antimalarial properties.

CHR-2797 is orally bioavailable and currently undergoing phase II clinical investigation in the treatment of myeloid leukemia.

Therefore, a safe and orally bioavailable intervention for therapy of osteolytic bone resorption is still a clinically unmet need.

Thus, apixaban is an orally bioavailable inhibitor of factor Xa with elimination pathways that include metabolism and renal excretion.

VX-787 is a first in class, orally bioavailable compound that offers unparalleled potential for the treatment of pandemic and seasonal influenza.

We previously described a regulatory system that enables transcription of a target gene to be controlled by rapamycin, an orally bioavailable drug.

IQN17 and these D-peptide inhibitors are likely to be useful for development and identification of a new class of orally bioavailable anti-HIV drugs.

Context: MK-5442 is an orally bioavailable calcium-sensing receptor antagonist that is hypothesized to stimulate bone formation by stimulating endogenous secretion of a pulse of PTH.

Compound 3 has provided a significant stepping stone towards the discovery of the orally bioavailable B 2 antagonist PHA-022121, currently in phase 1 clinical development.

In an effort to obviate these challenges, we set out to develop an orally bioavailable, selective Na V 1.7 inhibitor, lacking these acidic functional groups.