Exercise training reduced body weight, plasma insulin, and oxidized LDL concentrations.

The same antibody induced an increase in monocyte binding and uptake of oxidized LDL.

Oxidized LDL are independent predictors of subclinical and clinical atherosclerosis.

We injected newborn apoE KO mice with oxidized LDL.

However, oxidized LDL does accumulate within arterial lesions.

This suggests that both T cell-dependent and T cell-independent epitopes may be present on oxidized LDL.

Release of fructose and hexose phosphates from vascular endothelial cells was also induced by oxidized LDL.

Oxidized LDL and its receptor OLR1 may play a role in a proinflammatory phenotype in PAH.

PPE suppressed the oxidized LDL-induced foam cell formation by blocking the induction of scavenger receptor B1.

Conclusions: These findings suggest that antibodies are important mediators of atheroprotective immune responses directed to oxidized LDL.

Increased oxidized LDL-C was associated with a 7.93-fold increased risk for migraine.

Thus, C. pneumoniae augments the effects of oxidized LDL on cell death independent of a sustained infection.

Oxidized LDL is highly atherogenic, as it stimulates foam cell formation and promotes inflammatory and thrombotic processes.

Consonant with this hypothesis, HOCl oxidized LDL cholesterol in the presence of Cl- and at acidic pH.

Both cytotoxicity and HO-1 inducing ability of the oxidized LDL were strongly dependent on its lipid hydroperoxide content.

This suggests that rare ether-linked phospholipids in LDL are the likely source of PAF-like activity in oxidized LDL.