Intriguingly, the hedgehog signaling pathway also acts to promote development of the prethalamus.
2
Zic2a repression of six3b is essential for the correct formation of the prethalamus.
3
Neural Shh is essential for the development of the prethalamus (ventral thalamus), but its effects on the thalamus (dorsal thalamus) are still unclear.
1
In addition, these findings support the hypothesis that ventral telencephalic neurons and their axons guide TCAs through ventralthalamus and into ventral telencephalon.
2
Neural Shh is essential for the development of the prethalamus ( ventralthalamus), but its effects on the thalamus (dorsal thalamus) are still unclear.
3
A proportion of TCAs do extend further distally into ventralthalamus, but many of these stall at an aberrant, abrupt border of high RPTP(delta) expression.