Meanings of pharmacological characterization in английском

Therefore, further pharmacological characterization was conducted to fully understand its biological profile.

Moreover, the synthesis and the pharmacological characterization were extended to the corresponding univalent ligands.

We used a diversity-oriented synthetic approach and developed a library of PLD inhibitors with considerable pharmacological characterization.

In summary, we present the first report on the pharmacological characterization of a selective, potent and rodent-active small molecule CCR2 antagonist.

In this study, we describe the synthesis and pharmacological characterization of the first class of inverse agonists acting on the HCMV-encoded receptor US28.

Our pharmacological characterization of mouse TA1 showed that, as in rat and primate, amphetamine is an agonist at this receptor but with surprisingly high potency.

Then the pharmacological characterizations of the product were studied by receptor binding assay and cAMP assay.

Pharmacological characterization of known Kir7.1 inhibitors was also carried out and analogues of VU590 tested to assess selectivity at Kir7.1.

Strikingly, no or very weak affinity were found for muscarinic receptors, highlighting that pharmacological characterizations of venom-purified peptides may be risky due to possible contaminations.