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The consequences are profound for targeting and possibly systemic delivery of cationic lipidic-polynucleotide complexes.
2
The amount they migrate is dependent on the size and shape of each polynucleotide.
3
Our results suggest that the HCV core polynucleotide warrants further investigation as a potential vaccine against HCV infection.
4
Multiple sequence alignments revealed unexpected homologies between the Gifsy-I Xis protein and two distinct subsets of polynucleotide binding proteins.
5
This reagent was prepared by polymerizing a mixture of ADP and 8-N3-ADP with polynucleotide phosphorylase.
6
Imagine that the gel acts as a sort of sieve, the bigger the polynucleotide the less distance it will migrate.'
7
The cytidine analogue 5-methylcytidine also occurs in both DNA and RNA, but is introduced at the polynucleotide level in both cases.
8
RNAs must fold into unique three-dimensional structures to function in the cell, but how each polynucleotide finds its native structure is not understood.
9
Thus, hairpin dynamics are strongly coupled to solvent viscosity, indicating that diffusion of the polynucleotide chain through the solvent is involved in the rate-determining step.
10
From the polynucleotide sequence of the gene, a molecular mass of 12.9 kDa was calculated and hence we predict a homodimeric quaternary structure.
11
The polynucleotides are charged so they'll migrate, or move, in the electric field.
12
Susceptibility to digestion with nuclease S1 also suggested differences in the conformations of the two modified polynucleotides.
13
'So in the gel matrix you get separation of polynucleotides into different bands.
14
'It will take several hours now for the polynucleotides to migrate in the gel matrix.
15
Studies with synthetic oligo- and polynucleotides with specified sequence elements showed that exonuclease V cleaves off dinucleotides as primary digestion products.
16
A possible new way to obtain the statistical weights of elementary nucleotide arrangements is by single-macromolecular mechanical measurements on specifically designed polynucleotides.