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We developed methods for culture of cardiocytes from zebrafish embryos and found that, even in culture, cells from smo continue to beat relatively slowly.
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The peculiarity of smo....
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Thus, the differential phosphorylation of Smo mediates the thresholds of Hh activity.
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In addition, little is known about whether ubiquitination is involved in Smo regulation.
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Smo inhibitor particularly blocked the formation of hypertrophic chondrocytes and collagen type X expression.