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In the adult cochlea, EGFR transcripts were detected only in the spiralganglion.
2
The temperature in the spiralganglion cells increases as a result of photon absorption.
3
The morphology of spiralganglion cells and hair cells appeared normal throughout the cochlea.
4
Furthermore, cochlea-specific Gata2 deletion mice also had fewer spiralganglion cells and resultant hearing impairment.
5
GR receptor mRNAs were demonstrated in spiral ligament cells, spiral limbus cells, and spiralganglion cells.
6
There was disruption of the organ of Corti and spiralganglion cells in 4 temporal bones.
7
Histopathological evaluation revealed more serious damage in the spiralganglion and brainstem tissues of female rats.
8
Damage to the sensory hair cells and the spiralganglion neurons of the cochlea leads to deafness.
9
In mouse cochlea, expression of DMXL2 was restricted to the hair cells and the spiralganglion neurons.
10
Age-dependent alterations in Kir4.1 immunostaining also were observed in satellite cells ensheathing spiralganglion neurons.
11
These results show that GATA2 and GATA3 redundantly function to maintain spiralganglion cells and hearing.
12
The cochleae of the null mice had severe spiralganglion cell degeneration at 7-9 months of age.
13
This difference in hearing can be attributed to the more severe damage seen in neuronal tissues such as spiralganglion cells and brainstem neurons.
14
The stereocilia of cochlear hair cells are disorganized and splayed in mutant mice, with subsequent degeneration of the hair cells and spiralganglion cells.
15
The decrease in spiralganglion cellularity was associated with lowered expression of neurotrophin receptor TrkC that is an essential factor for spiralganglion cell survival.