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Mortality rates in the intensive care unit are not decreased by stressulcer prophylaxis.
2
Acid-suppressive therapy for prophylaxis of stressulcer bleeding is commonly prescribed for hospitalized patients.
3
The practice of routine administration of acid-suppressive drugs to critically ill patients for stressulcer prophylaxis warrants further evaluation.
4
We hypothesise that stressulcer prophylaxis reduces the rate of gastrointestinal bleeding, but increases rates of nosocomial infections and myocardial ischaemia.
5
Purpose: To examine the differential effect of stressulcer prophylaxis on overt bleeding, clinically important bleeding, and mortality in critically ill patients.
6
Purpose of review: Stressulcer prophylaxis (SUP) is considered standard of care in the majority of critically ill patients in the ICU.