Significats de bone tumour en anglès

Background: Prosthetic reconstruction may be a promising treatment for peri-acetabular malignant bone tumour; however, it is associated with a high complication rate.

Herein we investigated the genetic events of 17 GCTBs including benign and malignant variants and the methylation profiles of 122 bone tumour samples including GCTBs.

Reports of primary sacral bone tumours in children are scarce.

Primary bone tumours and tumour-like lesions in children have not been reported from Zaria.

The purpose of this paper is to describe 16 children with primary sacral bone tumours.

All sacral bone tumours, with the exception of Ewing's sarcoma are very rare in childhood.

Conclusion: This study has shown that, primary bone tumours are relatively uncommon in children in our setting.

Material and methods: We performed a descriptive, retrospective, cross sectioned clinical trial in the Bone Tumour Department.

There were 23 primary malignant bone tumours, four metastatic tumours and four locally advanced primary tumours of the rectum.

Osteosarcomas are aggressive bone tumours with a high degree of genetic heterogeneity, which has historically complicated driver gene discovery.

The use of extendible distal femoral replacements is a relatively new treatment alternative for malignant bone tumours in growing individuals.

Unsupervised clustering of DNA methylation profiles revealed that malignant H3.3-mutated tumours are distinct from their benign counterpart, and other bone tumours.

Materials and methods: A retrospective review of histopathology reports of 40 children with bone tumours and tumour-like lesions in 11 years of age.

Methods: We retrospectively analyzed 11 patients with peri-acetabular malignant bone tumours treated by personalized 3D-printed hemipelvic prostheses after en bloc resection between 2015 and 2016.