Significats de cirrhotic animals en anglès

Progenitor cell expansion was most prominent in cirrhotic animals, and correlated with transcript levels of pro-fibrotic genes.

Blood cell suspension or monocytes from cirrhotic animals, but not from controls, induced arterial hypotension in recipient rats.

Results: In response to incremental increases in flow, cirrhotic animals produced significantly less NO(x) than control animals.

In the aorta from cirrhotic animals, both nNOS protein expression and cGMP concentration were significantly elevated compared with control.

Increased plasma arginine vasopressin concentrations in the cirrhotic animals were also repressed with 7-NI in association with diminished water retention.

NOS activity was significantly reduced in liver tissue from cirrhotic animals compared with control animals in the presence of similar eNOS protein levels.

Results: CB1 receptor blockade did not modify systemic hemodynamics in control rats, but significantly increased arterial pressure and peripheral resistance in cirrhotic animals.

Cirrhotic animals had a significant increase in water and sodium retention.