Encara no tenim significats per a "corneal innervation".
1Purpose: To describe corneal innervation and trigeminal alterations in drug-naive patients with Parkinson disease (PD).
2His 78-year-old mother showed more advanced changes with dense crystals, highly fibrotic stroma, and severely damaged corneal innervation.
3Confocal corneal innervation analysis might provide possible early biomarkers for a better PD evaluation and for its earlier diagnosis.
4Results: Patients with PD showed profound alterations of corneal innervation and of trigeminal diffusion MRI parameters, compared with controls.
5Conclusions: Corneal innervation changes might occur earlier in patients with PD than in retinal ones.
6Corneal innervation parameter changes were evaluated in vivo using the Confoscan 4 confocal microscope, and they were compared with a control data set.
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