Meanings of corneal innervation in inglês

Purpose: To describe corneal innervation and trigeminal alterations in drug-naive patients with Parkinson disease (PD).

His 78-year-old mother showed more advanced changes with dense crystals, highly fibrotic stroma, and severely damaged corneal innervation.

Confocal corneal innervation analysis might provide possible early biomarkers for a better PD evaluation and for its earlier diagnosis.

Results: Patients with PD showed profound alterations of corneal innervation and of trigeminal diffusion MRI parameters, compared with controls.

Conclusions: Corneal innervation changes might occur earlier in patients with PD than in retinal ones.

Corneal innervation parameter changes were evaluated in vivo using the Confoscan 4 confocal microscope, and they were compared with a control data set.