Significats de cyclic peptides en anglès

The resulting cyclic peptides are cell permeable and have improved proteolytic stability.

Peptide thioesters serve as fundamental building blocks for the synthesis of proteins and cyclic peptides.

Measurements made in the presence of verapamil showed that the cyclic peptides experienced a ca.

However, the MSDIN gene family encoding for these cyclic peptides in A. fuligineoides has not been systematically studied.

However, their applications against intracellular targets have been limited, because cyclic peptides are generally impermeable to the cell membrane.

To improve the biological properties, 10 cyclic peptides (cPs) were designed from the lead peptides and synthesized.

The Compstatin family of cyclic peptides blocks complement activation at the C3 cleavage step, and is under investigation for treatment of complement-mediated diseases.

Alternatively, cyclic peptides were prepared with stable polyethylene glycol bridges across internal lysine residues of modified antigenic peptides such as KQPFPEKELPY and LQLQPFPQPEKPYPQPEKPY.

We report on the design and evaluation of novel cyclic peptides targeting the N-terminal domain of the protein tyrosine phosphatase YopH from Yersinia.

Fusion of cyclic peptides with a cyclic cell-penetrating peptide produces bicyclic peptides that are cell-permeable and retain the ability to recognize specific intracellular targets.

The effect of cyclization as well as the length of the spacer in the cyclic peptides on DQ2 binding and T cell recognition was analyzed.

These cell-permeable cyclic peptides inhibit Ras signaling by binding to Ras-GTP and blocking its interaction with downstream proteins and they induce apoptosis of cancer cells.

Herein we present a method for the combinatorial synthesis and screening of large one-bead-one-compound (OBOC) libraries of cyclic peptides against biological targets such as proteins.

Cyclic peptides have great potential as therapeutic agents and research tools.

Cyclic peptides have been a rich source of biologically active molecules.

Cyclic peptides (CPs) are an exciting class of molecules with a variety of applications.