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Significats de cyclin-dependent kinase en anglès

rus
циклин-зависимые киназы
espanyol
kinasa dependiente de ciclinas
català
quinasa dependent de ciclina

Class of enzymes.

        Termes relacionats
        quinasa dependent de ciclina
        Sinònims
        Examples for "cdk"
        Examples for "cdk"
        1
        Deregulated expression of G1 cyclins and their cognate cdk partners is often found in human tumor cells.
        Pubmed
        2
        These findings argue against the proposed necessity of complete Rb inactivation by sequential phosphorylation by D- and E-type cyclin-cdk complexes.
        Pubmed
        3
        We have studied the role of a conserved hydrophobic patch on the surface of cyclin A in substrate recognition by cyclin A-cdk2.
        Pubmed
        4
        In addition, the concomitant expression of Np95 and of cycE-cdk2 was alone sufficient to induce S phase in TD cells.
        Pubmed
        5
        Shortening of G1 phase temporally correlated with more rapid degradation of the cdk inhibitor p27Kip1 and with premature activation of cyclin A-dependent cdk2.
        Pubmed
        Ús de cyclin-dependent kinase en anglès
        1
        Purpose: Flavopiridol is the first cyclin-dependent kinase inhibitor to enter clinical trials.
        Pubmed
        2
        The results implicate a putative cyclin-dependent kinase in the control of development.
        Pubmed
        3
        The other three mutants caused phenotypes dependent on the particular cyclin-dependent kinase.
        Pubmed
        4
        Cdc2 is the cyclin-dependent kinase that controls entry of cells into mitosis.
        Pubmed
        5
        D-type cyclin-dependent kinase activities have not so far been detected in mammalian cells.
        Pubmed
        6
        A major determinant of Acm1 stability is phosphorylation at consensus cyclin-dependent kinase sites.
        Pubmed
        7
        Finally, the effects of cyclin-dependent kinase inhibitors on dihydrofolate reductase gene expression were evaluated.
        Pubmed
        8
        The expression of cyclin-dependent kinase inhibitor p21 is dramatically increased in the mutant embryos.
        Pubmed
        9
        CF neutrophils formed more NETs and this was reversed by cyclin-dependent kinase inhibitor exposure.
        Pubmed
        10
        Purpose: Flavopiridol is a cyclin-dependent kinase inhibitor that prevents cell cycle progression and tumor growth.
        Pubmed
        11
        Interestingly, this response was self-limited at later developmental time points by an upregulation of the cyclin-dependent kinase inhibitor p21.
        Pubmed
        12
        Despite its partial structural similarity with the cyclins, p25 displays an unprecedented mechanism for the regulation of a cyclin-dependent kinase.
        Pubmed
        13
        The expression of the transcription factor Sp1, a retinoblastoma-interacting protein, was also enhanced by all the cyclin-dependent kinase inhibitors tested.
        Pubmed
        14
        These compounds exhibited potent inhibitory activity against cyclin-dependent kinase 4 and good antiproliferative activity in a human colon carcinoma cell line.
        Pubmed
        15
        Ibrance works by blocking two enzymes, cyclin-dependent kinase 4 and 6, that are involved in cell growth.
        Reuters
        16
        Treatment with the cyclin-dependent kinase inhibitor SCH727965 alone or in combination is a highly promising novel experimental therapeutic strategy against pancreatic cancer.
        Pubmed