Significats de efflux pump en anglès

Furthermore, they showed no potential to induce the transmembrane efflux pump P-gp.

The presence of efflux pump genes was analyzed using polymerase chain reaction.

Another reason of drug tolerance is the efflux pump of the bacterium.

Chemoresistance has also been variably linked to the drug efflux pump p-glycoprotein.

In addition, 1167 increased the intracellular concentration of chloramphenicol in efflux pump-overproducing strains.

This efflux pump inhibitory activity was further confirmed by time-kill experiments.

RT-qPCR assessment of efflux pump genes expression showed overexpression of all tested genes.

P-glycoprotein is a transmembrane protein thought to function as an efflux pump to detoxify cells.

The L22 mutation conferred reduced erythromycin susceptibility in the drug efflux pump proficient, but not deficient, background.

The MIC increase is associated with an overexpression of an efflux pump immunorelated to AcrAB-TolC in various variants.

Consistent with the operation of an efflux pump, expression of MRP7 reduced the accumulation of Ara-C and PMEA.

Expression levels of efflux pump genes and regulators were examined by quantitative real-time reverse transcription polymerase chain reaction.

ABCG2 is a multidrug efflux pump associated with resistance of cancer cells to a plethora of unrelated drugs.

Four novel inhibitors of the NorA efflux pump of Staphylococcus aureus, discovered through a virtual screening process, are reported.

We identified unique SNPs in efflux pump genes which may be associated with increased drug resistance in the isolates.

P-glycoprotein is believed to function as an energy-dependent efflux pump that is responsible for decreased drug accumulation in multidrug-resistant cells.