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Furthermore, they showed no potential to induce the transmembrane effluxpump P-gp.
2
The presence of effluxpump genes was analyzed using polymerase chain reaction.
3
Another reason of drug tolerance is the effluxpump of the bacterium.
4
Chemoresistance has also been variably linked to the drug effluxpump p-glycoprotein.
5
In addition, 1167 increased the intracellular concentration of chloramphenicol in effluxpump-overproducing strains.
6
This effluxpump inhibitory activity was further confirmed by time-kill experiments.
7
RT-qPCR assessment of effluxpump genes expression showed overexpression of all tested genes.
8
P-glycoprotein is a transmembrane protein thought to function as an effluxpump to detoxify cells.
9
The L22 mutation conferred reduced erythromycin susceptibility in the drug effluxpump proficient, but not deficient, background.
10
The MIC increase is associated with an overexpression of an effluxpump immunorelated to AcrAB-TolC in various variants.
11
Consistent with the operation of an effluxpump, expression of MRP7 reduced the accumulation of Ara-C and PMEA.
12
Expression levels of effluxpump genes and regulators were examined by quantitative real-time reverse transcription polymerase chain reaction.
13
ABCG2 is a multidrug effluxpump associated with resistance of cancer cells to a plethora of unrelated drugs.
14
Four novel inhibitors of the NorA effluxpump of Staphylococcus aureus, discovered through a virtual screening process, are reported.
15
We identified unique SNPs in effluxpump genes which may be associated with increased drug resistance in the isolates.
16
P-glycoprotein is believed to function as an energy-dependent effluxpump that is responsible for decreased drug accumulation in multidrug-resistant cells.