Significats de formalin test en anglès

Main methods: The formalin test was used to assess the nociceptive activity.

The antinociceptive effect of compound 1 was determined using the formalin test.

The formalin test was used to assess the nociceptive activity.

Local administration of meloxicam produced a dose-dependent antinociception in the second phase of the formalin test.

Local administration of diclofenac produced a significant antinociception in both phases of the formalin test in female Wistar rats.

The antinociceptive activity of an inhibitor of phosphodiesterase 5, alone or combined with diclofenac, was assessed in the formalin test.

The purpose of this study was to assess the possible synergistic interaction between ketorolac and B-vitamins in the rat formalin test.

Estradiol significantly decreased nociceptive responses in OVX rats with effects during both the first and the second phase of the formalin test.

B. garcibarrigae presented significant effect on the early phase of the formalin test, pointing to an antinociceptive mechanism distinct from traditional anti-inflammatory medicines.

Experiment 2 showed a similar shift from antinociception to nociception on the formalin test in mice immediately after removing them from the EPM.

The present work assessed the possible participation of K+ channels in the peripheral antinociceptive action of metamizol in the 1% formalin test.

The present study assessed the possible pronociceptive role of peripheral and spinal 5-HT(6) receptors in the formalin test.

The effects of individual and fixed-ratio combinations of locally (subcutaneous) and systemically (intraperitoneal) dosed tramadol were evaluated using the formalin test in rats.

The involvement of the nitric oxide-cyclic GMP pathway in the antinociceptive action of the cyclooxygenase-2 preferential inhibitor meloxicam was assessed in the rat formalin test.

Data also suggests that mangiferin activates the NO-cyclic GMP-ATP-sensitive K(+) channels pathway in order to produce its local peripheral antinociceptive effect in the formalin test.

Our results suggest that 5-HT(6) receptors play a pronociceptive role in peripheral as well as spinal sites in the rat formalin test.