Meanings of null allele in anglès

We conclude that the C282Y mutation does not result in a null allele.

Mice containing Cre recombined conditional alleles phenocopy the previously characterized Thoc1 null allele.

To determine Scx function, we produced a mutant null allele.

Therefore, we have generated a hypomorphic allele of Rad51c in addition to a null allele.

The first mutation deletes a large portion of the coding sequence, generating a null allele.

We used gene targeting in embryonic stem cells to introduce an IL-1 beta null allele in mice.

We now present detailed functional analyses of Zfp281 using a genetically ablated null allele in mouse ESCs.

Here we have studied ADAR2-mediated RNA editing by generating mice that are homozygous for a targeted functional null allele.

The wide prevalence of this null allele in this population is probably due to the effects of a small founder population.

Similar circumstances existed when the CMAH null allele was polymorphic in ancestral hominins, just before the divergence of Homo from australopithecines.

A null allele of yeast CCP1 gene encoding CcP was created by one-step gene disruption method in a diploid yeast strain.

Furthermore, suppression was not observed when the suppressor allele was present on a plasmid and the chromosomal dnaA was a null allele.

We have generated a null allele of the mouse Msx1 homeobox gene by insertion of an nlacZ reporter gene into its homeobox.

Consistent with these phenotypes, mice carrying the fgfr1 null allele survived significantly longer than those without fgfr1 deletion.

GSTT1 null allele frequency was 45.78%, which was significantly higher than that in Caucasians and African-American.

In a gene trap screen we recovered a mouse mutant line in which an insertion generated a null allele of the Brd4 gene.