Meanings of pharmacogenetic studies in anglès

To date, the majority of pharmacogenetic studies have been performed using germline DNA.

Yet to date there have been no pharmacogenetic studies of BDNF in ADHD.

However, the common problem in pharmacogenetic studies is the availability of samples, often limited.

Candidate gene pharmacogenetic studies offer a strategy for the rapid assessment of putative predictive markers.

DNA collection in most clinical trials provides a wealth of samples from which pharmacogenetic studies can be launched.

Prospective pharmacogenetic studies are warranted to continue investigation of the impact of IDO polymorphisms on the development of IFN-a-induced depression.

This has prompted pharmacogenetic studies, mostly with regard to their dose-concentration relationships, but also about proteins involved in their pharmacodynamics.

Although risperidone belongs to the first-line atypical anti-psychotics, there have been relatively few risperidone pharmacogenetic studies, especially in Asian populations.

Different types of pharmacogenetic studies may improve our understanding of the functional consequence of a genetic variant in the clinical setting.

These results provide experimental validation and estimated allele frequencies for polymorphisms in three common ethnic groups and facilitate applied pharmacogenetic studies of anticancer drugs.

Available data, as well as previous pharmacogenetic studies, suggest that genetics may contribute as much as 60-80% to the interindividual variability in treatment response.

Pharmacogenetic studies investigating folate-related drug targets in the treatment of colorectal cancers and hematologic malignancies will subsequently be discussed.

Pharmacogenetic studies attempt to discover and estimate the contributions of genetic variants to the variability in response to a drug treatment.