Significats de placental inflammation en anglès

Preterm infants exposed to severe placental inflammation have an increased risk of brain injury.

The determinants of adverse health outcomes among HEU children are poorly understood but may result from chronic placental inflammation (CPI).

ZIKV inoculation at E10 causes placental inflammation, placental dysfunction and reduces neonatal brain cortical thickness, which is associated with increased activation of microglia.

Cord blood IL-8, TNF-a and G-CSF may be involved in the process of brain injury in preterm infants with placental inflammation and FIRS.

Objective: We studied whether magnetic resonance imaging (MRI) could be used to detect placental inflammation before the detection of irreversible tissue damage.

Thus, local induction of TLR signaling via saturated fatty acids (SFA) may in part contribute to placental inflammation in diet-induced maternal obesity.

The placental inflammation was confirmed by HCA, and FIRS was defined in fetuses with preterm labor and an elevation of the fetal plasma interleukin-6 concentration.

The grade 2 and grade 3 of placental inflammation and the inflammation at stage 2 and stage 3 increased the risk of brain injury.

Placental inflammation was assessed by determination of the levels of inflammatory cytokines.

Conclusions: Placental inflammation and FIRS are associated with brain injury in preterm infants.

Results: Placental inflammation was detected by MRI as early as 3 hours after maternal administration of lipopolysaccharide, concomitantly to IL-1β up-regulation.