A rare brain and spinal cord disease caused by a virus and usually seen only in immunocompromised individuals, such as those with HIV.
1Last month Biogen said a fourth patient in Europe had developed PML.
2However, the basis for such a structural role of PML is unknown.
3The average number of infusions received before diagnosis of PML was 25.
4In particular, PML and p53 showed considerable potential as independent prognostic markers.
5Dozens of patients undergoing treatment with Tysabri have been diagnosed with PML.
6Four cases of PML have been diagnosed since the drug was reintroduced.
7The PML gene was rarely mutated and was not subject to LOH.
8Tysabri was withdrawn from the market in 2005 after three patients developed PML.
9Privately, military sources accused the PML-N of deliberately trying to undermine the army.
10Then, at the end of July, two more cases of PML were reported.
11Continued evaluation of anti-JCV antibody index and PML risk is warranted.
12We believe this is the first antemortem description of PML after liver transplantation.
13Survival of AIDS-related PML is improved by HAART when JCV replication is controlled.
14The PML tumor suppressor controls growth suppression, induction of apoptosis, and cellular senescence.
15PML mRNA was expressed in all tumor and cell line samples.
16PML degradation was also observed in SK-BR3 breast cancer cells treated with RA.