A gene that suppresses the phenotypic expression of another gene (especially of a mutant gene)
1The NF1 gene is a classic example for a tumour suppressor gene.
2Thus, DCC represents the most promising candidate tumor suppressor gene from 18q.
3The tumor suppressor gene p53 is activated by reactive oxygen species-generating agents.
4These data strongly support the hypothesis that BRCA1 is a tumor suppressor gene.
5Objective: To determine the expression of tumor suppressor gene PRDM1 in lung cancers.
6These data suggest that Tes functions as a tumor suppressor gene in vivo.
7The TP53 tumor suppressor gene is mutated in the majority of human cancers.
8These observations have led to classify LKB1 as tumour suppressor gene.
9This suggests that a tumor suppressor gene maps in this region.
10Hypermethylation-mediated tumor suppressor gene silencing plays a crucial role in tumorigenesis.
11Mutations in the VHL tumor suppressor gene predispose individuals to highly vascularized tumors.
12PTEN is a tumor suppressor gene that is frequently mutated in human tumors.
13Whereas a putative tumor suppressor gene, we did not detect AJAP1 gene mutations.
14The nm23 gene is a putative tumour and metastasis suppressor gene.
15Inactivation of the tumor suppressor gene p53 is frequently associated with ovarian cancer.
16The p53 tumor suppressor gene frequently is mutated in many forms of human carcinomas.
Translations for suppressor gene