The prognosis of infants with truncus arteriosus associated with severe truncal valve insufficiency is quite poor.
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In the current era interrupted aortic arch is no longer a risk factor for repair of truncus.
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Conclusion: Despite the magnitude of the operation, excellent results can be achieved in complex forms of truncus arteriosus.
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Objective: Truncal valve regurgitation and interrupted aortic arch have frequently been identified as risk factors in the repair of truncus arteriosus.
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Congenital heart diseases such as single ventricle, truncus arteriosus, transposition of the great arteries and tetralogy of Fallot are also associated with aortic medial abnormalities.
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The first human mutations in GATA6 were described in a cohort of patients with persistent truncus arteriosus, and the phenotypic spectrum has expanded since then.
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Results: Model-estimated risk of major complications ranged from 1.0% for simple procedures to 38.2% for truncus arteriosus with interrupted aortic arch repair.