Significats de unstressed cells en anglès

In unstressed cells, p53 is maintained at low levels by the ubiquitin-proteasome pathway.

In this study, we demonstrate that IRE1a interacts with BiP in unstressed cells and dissociates from BiP in the course of cartilage development.

In unstressed cells, DnaK localizes to multiple, dynamic foci, but relocalizes to focal protein aggregates during stationary phase or upon expression of aggregating peptides.

This effect is mirrored by enhanced p53 protein levels in both unstressed cells and cells exposed to p53-activating stress agents.

These data indicate that JFK is a critical negative regulator of p53 and represents a pathway for the maintenance of p53 levels in unstressed cells.