Meanings of cloned mice in English

Here, we report the production of cloned mice from urine-derived cells collected noninvasively.

The results suggest that these cloned mice had normal fertility.

Healthy cloned mice were then produced from these nuclear transferred embryonic stem cells by serial nuclear transfer.

Activity level, motor ability and coordination, and learning and memory skills of cloned mice were comparable with controls.

Heterozygosity of the donor ES cell genome has been suggested as a crucial factor for long-term survival of cloned mice.

Increased body weight was attributable to higher body fat and was associated with hyperleptinemia and hyperinsulinemia indicating that cloned mice are obese.

These studies represent the first comprehensive set of data to characterize cloned mice and provide critical information about the long-term effects of somatic cell cloning.

Here we report production of cloned mice from bodies kept frozen at -20 degrees C for up to 16 years without any cryoprotection.

Cloned mice were not hyperphagic as adults and had hypersensitive leptin and melanocortin signaling systems.